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The hydroxyl group is highly hydrophilic so the drug undergoes the process of phase II metabolism readily

It was found that the resistant cultivar Puangmanee, as compared with susceptible cultivars Monthong and Kradumthong, significantly expressed genes encoding chitin response proteins such as lysM domain receptor-like kinase and endochitinase

~ AlphaMD Most men on testosterone replacement therapy obsess over total testosterone levels, but the real culprit behind many frustrating side effects might be a lesser-known hormone derivative called DHT

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If there are complicating medical or untreated comorbidities some patients will be in therapy longer.