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Given the evidence that a pulsatile pattern of GH secretion is important for many of its physiological actions, a strategy to augment physiological pulsatile GH secretion without inducing the side-effects of supraphysiological GH doses has been studied in HIV lipodystrophy with excess VAT and decreased endogenous GH secretion (144, 145)

After stroke, the EE caused increased dendritic growth, enhanced sensorimotor recovery, increased synaptic plasticity and production of trophic factors, as well as reduced apoptosis (Geibig et al., 2012)

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