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So, as this group has been experimenting over the last years, the problem with IGF-1 is a matter of dosage

They have demonstrated efficacy in alleviating pain associated with diabetic neuropathy, neuralgia, and low back pain, as well as promoting nerve conduction, making them beneficial for a variety of neurological and pain-related conditions

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Therefore, even though B12 may come in more concentrated dosages with oral administration, the IM shots still provide the best way to correct B12 deficiency