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When people quit smoking, they might feel anxious or experience withdrawal symptoms as their brain and body adjust to not having nicotine around

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However, if a manufacturer did not submit the SE report before March 23, 2011, or if the new tobacco product has been on the market since March 22, 2011, the product is not permitted to be marketed without an SE order from FDA, even if FDA takes longer than 90 days to approve and issue the order

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