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Each temperature excursion reduces that window proportionally: a vial exposed to room temperature for 6 hours loses approximately 34 days of viable shelf life

624 , 625 Among caregivers of people with dementia who have experienced severe psychiatric symptoms (e.g., aggression or anxiety), those who live in low or mediumincome neighborhoods indicate higher distress than those living in highincome neighborhoods

(-80C is more effective)

To help bridge this gap, risk stratification tools have been developed on the basis of clinical parameters (eg, male sex, cigarette smoking, older age, and length of BE segment)