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In a head-to-head open-label trial reported in February 2026, average weight loss at 84 weeks favored tirzepatide, and the sponsor noted CagriSema did not meet its prespecified non-inferiority target against tirzepatide

xCT-driven expression of GPX4 determines sensitivity of breast cancer cells to ferroptosis inducers

R., Folmes, C

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We cannot exclude the possibility that loss of fluorescence during AITC treatment was due to its interference with the biomarker, but it has been reported that exogenously supplied chemicals responsible for GSH depletion are not likely to interfere with roGFP2 52