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From the laboratory of Jin Wang, PhD, Baylor College of Medicine

Lysine biosynthesis and sulfur metabolism were not regulated by XJZ-A after XJZ subtracted the assistant drug, suggesting that the assistant drug plays a major role in the regulation of the above 2 metabolic pathways by XJZ

In some of such embodiments, the formulations or compositions or devices described herein are administered via direct cochlear injection, through a cochleostomy or via deposition on the round window