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This cluster encodes gliP , a bimodular nonribosomal peptide synthetase (NRPS) which has been conclusively shown to be responsible for the biosynthesis of a Phe-Ser dipeptide, a gliotoxin precursor, by gene disruption ( gliP mutant) [9][12]

and (3) Gene therapy approaches that correct the defective lysosomal cystine transport in parenchymal cells

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In OCD, early case reports suggested benefit from memantine augmentation of standard SSRI pharmacotherapy in refractory adults (Pasquini & Biondi, 2006

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