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AMPT exerts its inhibitory actions on tyrosine hydroxylase, which will lead to a severe impairment in the endogenous production of dopamine [25, 31]

) Summary and Conclusions Genetic variation in folate metabolism has emerged as a critical area of investigation, not only for its role in rare hereditary disorders but for its far-reaching implications in common, multifactorial conditions such as cardiovascular disease, birth defects, cancer, and neurodevelopmental disorders

doi: 10.1016/j.neuroscience.2019.08.050 69 ConnorAMMahomedNGandhiRKeystoneECBergerSA

This excess doesn't necessarily translate to proportionally better results

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