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(PubMed) Rees K, Hartley L, Day C, Flowers N, Clarke A, Stranges S

Amino Acids 42 , 207219 (2012)

The following facts have been proven or are currently being discussed: Vitamin B1 (thiamine) does not have a direct effect on the skin, but its involvement in blood formation ensures rosy skin with good blood circulation Vitamin B2 (riboflavin) is important for keratinocytes and thus the skin barrier due to its positive effect on the fast-growing cells Niacin (vitamin B3) is an important vitamin for the protein metabolism, which is visible in the skin

The kidney eliminates circulating particles through the urine, while the blood-brain barrier (BBB) prevents their entry into the central nervous system

[2] The paradox of binding proteins and half-life There is an apparent paradox here that confuses many people first encountering the topic