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Who should avoid GHK-Cu: Patients with Wilson's disease (copper metabolism disorder), active liver disease, or who are pregnant or nursing

Without enough vitamin B12, the body may struggle to produce healthy red blood cells and maintain normal nerve function

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folic acid only, zinc only, a combination, and placebo.[30] After 26 weeks of treatment, a statistically significant increase in sperm concentration was noted among subfertile men receiving combination therapy