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As a dual amylin and calcitonin receptor agonist, cagrilintides mechanism of action centers on binding to the calcitonin receptor (CTR) and the amylin receptor subtypes AMYR, AMYR, and AMYR each formed by the CTR partnered with receptor-activity modifying proteins RAMP1, RAMP2, or RAMP3, respectively

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It involves spraying the peptide solution into the nasal passages, allowing for absorption through the nasal mucosa and into the bloodstream