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BV affects angiogenesis and neovascularization in diabetic mice by inhibiting caspase-3, -8, and -9 activity while enhancing TGF- and VEGF levels

Research demonstrates that BPC-157 upregulates VEGFR2 at both mRNA and protein levels in vascular endothelial cells without increasing VEGF-A itself, effectively sensitizing cells to existing VEGF in the tissue microenvironment rather than simply adding more growth factor signal

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