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Side effect profiles BPC-157: Generally well-tolerated

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But in the process, they generate reactive oxygen species (ROS), unstable molecules that can damage DNA, proteins, and lipids

To illustrate, a 2015 study showed that rats fed a collagen peptide absorbed more than 63% of the collagen, whereas other orally administered peptides have exhibited bioavailability rates as low as 1-2%.12 13 BPC-157 is an exception, too it remains stable in gastric juice for more than 24 hours, allowing it time to pass through the gastrointestinal walls15 but its often used in conjunction with the not-so-orally-bioavailable TB4

10.1083/jcb.200210110 J