Unlike a pure cell culture (where individual cells grow in a dish), ex vivo organ culture preserves the complete tissue structure in this case, whole hair follicles with all their cell types intact
While the exact causes of these erythrocyte changes are due to fibrin amyloid microclots or other factors, such as ROS (which can cause RBC changes as well [367, 368]), remain unclear, they likely contribute to the oxidative stress observed in Long COVID [369, 370]
While it can be obtained through food and supplements, not everyone can absorb adequate amounts through diet alone
doi: 10.1016/0090-6980(81)90123-4
In the extension of this study, they validated their proposal in vitro and in vivo and demonstrated that antiproliferative effects [428]