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10.1002/9780470122778.ch5 14 Chanut-DelalandeH.HashimotoY.Pelissier-MonierA.SpokonyR.DibA.KondoT.et al (2014)

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-gamma coactivator 1alpha regulated beta-secretase 1 degradation and mitochondrial gene expression in Alzheimers mouse models

Although IGF-I also has some neurotrophic effects, its main action is to promote muscle hypertrophy and activation of satellite cells via PI3K/AKT pathway