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Arthralgia and Psoriatic Arthritis: Arthralgia has been reported with the use of DUPIXENT with some patients reporting gait disturbances or decreased mobility associated with joint symptoms

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Thayaparan T, Petrovic RM, Achkova DY, Zabinski T, Davies DM, Klampatsa A, et al

The evidence is mixed, with some studies suggesting DSIP does not induce tolerance while user reports sometimes indicate diminishing returns with daily use

Skin Recovering From Environmental Stress Sun exposure, pollution, and other environmental factors can place significant stress on skin tissue