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Br J Clin Pharmacol 2025 demonstrates that co-infusing a GLP-1 agonist with glucagon produces a perfectly additive HR response (+4 bpm + +4 bpm = +7 bpm at 60 min in n=12 lean males), confirming that glucagon drives chronotropy via a parallel pathway independent of GLP-1R cross-reactivity

Plasma stability studies suggest BPC-157 is notably resistant to rapid proteolytic degradation in serum more resistant than many peptides of similar size

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Journal of Clinical Periodontology , 44 (2), 225-234