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there are also views that AD is an autoimmune disease, and that A is regarded as a cytokine and immune peptide with both immunomodulatory and antimicrobial properties

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2.1 Renal Impairment Study 2.1.1 Study Population Male and female participants of non-childbearing potential were eligible for inclusion in the renal impairment study if they were aged between 18 and 80 years with a body mass index (BMI) between 20 and 39.9 kg/m 2 and a body weight 60 kg at screening

Dose and exposure in the models are often high or non-physiologic