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The DiGeorge syndrome , also called velocardiofacial or 22q11.2 deletion syndrome (22q11.2DS), is caused by a hemizygous microdeletion (1.53 Mb) on chromosome 22 DiGeorge syndrome The prevalence rate of this condition is ~1 in 4000 [356]

Current recommendations suggest that cystatin C measurement be used in combination with creatinine testing to confirm kidney disease diagnosis in patients with reduced GFR (4559 mL/min) but no other signs of kidney damage (Shlipak, Mattes 2013)

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doi: 10.1073/pnas.1405023111 69 BolvarBEBrown-SuedelANRohrmanBACharendoffCIYazdaniVBelcherJDet al