See TB-500 for Tendon and Ligament Research
It is, in effect, the body's own copper-transport and tissue-signaling peptide: a simple three-amino-acid chain (glycine-histidine-lysine) with a very high natural affinity for copper ions, forming a stable complex that is easily studied and reproduced synthetically for laboratory use
The formula is: Daily sublingual dose = (Weekly injectable dose x Injectable bioavailability) / (7 days x Sublingual bioavailability) Using 80% injectable and 30% sublingual bioavailability as the midpoint estimate: Daily sublingual = (Weekly injectable x 0.80) / (7 x 0.30) = Weekly injectable x 0.38 This means a 10 mg weekly injectable dose translates to approximately 3.8 mg daily sublingual
Based on studies involving gene-targeted mice and cell culture experiments, the significance of AMP-activated protein kinase (AMPK), p21-activated kinase 2 (PAK2), cGMP-dependent protein kinase type I (cGKI), Janus kinase 3 (JAK3), mitogen and stress-activated protein kinase (MSK1/2), and phosphoinositide-dependent kinase 1 (PDK1) for eryptosis has been studied
J R Soc Interface (2022) 19(189):20210925
