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Moreover, metabolic reprogramming in immune cells, particularly mitochondrial dysfunction, has been linked to enhanced immune responses and tissue damage in SLE, further highlighting the role of hypoxia in driving autoimmune pathology (149)

Rosito M, Maqbool J, Reccagni A, Giampaoli O, Sciubba F, Antonangeli F, Scavizzi F, Raspa M, Cordella F, Tondo L, et al

Glutamine-addicted ccRCC tumors deprive the tumor microenvironment of glutamine

Escalation phase breakdown The standard protocol starts low and increases every four weeks to minimize gastrointestinal side effects that rapid dose escalation can cause

Wound healing and omega-6 fatty acids: from inflammation to repair