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Through stable isotope tracing and chromatin-immunoprecipitation (ChIP) assay, we also found that ACTL6A promotes GSH synthesis by upregulating the rate-limiting enzyme GCLC as a co-transcription factor

& Fussenegger, M

To put that in perspective, a 10 mg/kg dose in a 250-g rat, scaled allometrically to a 70-kg human using the FDA's body surface area conversion factor of 6.2, translates to roughly 1.6 mg/kg, or 112 mg for a 70-kg person 7

Your liver is also the primary organ responsible for detoxing the body and protecting your immune system from the wear-and-tear of harmful toxins and stress