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[ 412 ] Consistently, another research shows that SETD8 interacts with ELK1 to inhibit the transcription of BACH1, negatively regulating EndMT in diabetic nephropathy (DN), one of the most common complications among diabetic patients, which causes kidney failure

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Moreover, the structural similarity between vitamin K and ubiquinones suggests overlapping mechanisms of action, wherein FSP1-generated VKH 2 can mimic CoQ10H 2 in blocking ferroptosis in vitro (126)