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Sleep Regulation : Modulating circadian rhythms and normalizing sleep architecture ( 1, 2 )

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(99) demonstrated that Gpx4 expressed in myeloid cells plays a crucial role in lipid peroxidation, inflammasome activation, and release of DAMPs in the setting of sepsis, with Gpx4 deletion leading to increased lethality in sepsis conditions

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Systemic effects including cognitive benefits, mood regulation, and general tissue maintenance could work with either route, though injection delivers more predictable exposure levels