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Ipamorelin is highly selective for the ghrelin receptor and does not trigger the release of stress hormones (cortisol) or lactogenic hormones (prolactin)

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5.1.2 Impact on neurotransmitters and synaptic plasticity Chronic ketamine use disrupts the balance between excitatory and inhibitory neurotransmission

The common starting dose in community protocols is 100 mcg per shot, once daily at bedtime, on an empty stomach, for about one week