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MOST COMMON CARDIOVASCULAR DISEASES Ischemic heart disease, i.e., acute coronary syndromes, heart failure, cardiomyopathies, structural defects of the heart muscle, valvular defects, heart rhythm and conduction disorders Symptoms: The most common symptom of coronary artery disease is chest pain accompanied by a feeling of pressure and squeezing in the chest

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A study by Naidoo and colleagues showed that patients who received checkpoint inhibitor combination therapy tended to have a shorter onset time to adverse events than those who received checkpoint inhibitor monotherapy

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However, recent data revealed that the GF region also contributes to HSP70 binding, influencing the kinetics of HSP70-driven reactionsat least for HSC70 (Hobbs et al., 2025)