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When the mice were fed a diet deficient in choline, that is, lacking precursors required for DMG production, they failed to gain weight after smoking cessation. The second bioactive metabolite, acetylglycine, or ACG, followed a mirror-image pattern to that of DMG: Its levels were reduced during active exposure to smoke and after the exposure stopped, they increased following antibiotic treatment
Flavored Tobacco Product Use Among Middle and High School StudentsUnited States, 2014
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