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Third, the varenicline and placebo groups were not well-matched for anxiety and e-cigarette dependence levels

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Notably, the nicotine pharmacokinetic parameter C max , which is influential in an assessment of abuse liability and of a novel tobacco products potential to displace cigarette smoking 43,44,45,46,47,61 , is similar between the Pulze HTS and other types of HTPs 54,68

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