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Under strongly alkaline conditions, lignin forms reactive quinone-methide intermediates (chemistry not shown)

Furthermore, the hydrogen bond, which involves the conserved residue Asn419 hTrxR1 , is also present in structures of rat TrxR and TGR with a reduced C-terminal end

Funding This work was supported by a grant of Chonnam National University Hospital Biomedical Research Institute (BCRI22079, BCRI22042, and BCRI22046), and by the National Research Foundation of Korea (NRF) funded by the Korea Government (MSIT

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