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The best evidence of the positive effects of Ach on adult neurogenesis have come from studies that have performed cholinergic forebrain lesions which resulted in decreased proliferation, survival of NSCs, and new neurons in the dentate gyrus as well as deficits in learning and memory [134, 135]

Catalpol alleviates hypoxia ischemia-induced brain damage by inhibiting ferroptosis through the PI3K/NRF2/system Xc-/GPX4 axis in neonatal rats

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305 These results suggest that liver cells require a narrow window of SLC7A11 activity to maintain healthy liver function when exposed to a high-fat environment

Of note, no shifts in bone mineral density distribution were recorded