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In some embodiments, the otic formulation comprises between about 0.0001% to about 99.9999% by weight of the weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

Curcumin alters EpRE and AP-1 binding complexes and elevates glutamate-cysteine ligase gene expression

Despite a lack of precise correlates of protection, it is clear that a pan-coronavirus vaccine will need to induce immunity that cross-recognizes the full range of diversity across this viral family

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