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3.1 Regulation of glycolysis As mentioned above, key glycolytic enzymes such as HK, PFK, and PKM2, along with LDH, lactate transporters MCT1 and MCT4, and the glucose transporter GLUT1, are critical for tumor proliferation and metastasis

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This means they can penetrate the blood-brain (or blood-SCF) barrier and reach neurons directly, enabling the drug to exhibit organ-specific combined effects in the brain

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Social media algorithms also play a role here by amplifying positive testimonials, meaning those who had no response or experienced side effects using peptides are less likely to post about it