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Description

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

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Intestinal toxicity is a severe adverse effect associated with the administration of MTX, and patients are significantly burdened by MTX-provoked intestinal mucositis

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Abbreviations TT: Testicular torsion I/R: Ischemiareperfusion IR-I: Ischemiareperfusion injury PRP: Platelet-rich plasma PC: Post-conditioning LT: Left testis i.t: Intratesticular i.p: Intraperitoneally MDA: Malondialdehyde CAT: Catalase GSH: Reduced glutathione eNOS: Endothelial nitric oxide synthase HSP70: Heat shock protein 70 VEGF: Vascular endothelial growth factor TNF-: Tumor necrosis factor alpha IL-6: Interleukin-6 NF-B: Nuclear factor kappa B Bax: Bcl-2-associated X protein ROS: Reactive oxygen species PAS: Periodic acidSchiff H&E: Hematoxylin and eosin Hb: Hemoglobin RBCs: Red blood cells HCT (PCV): Hematocrit (packed cell volume) MCV: Mean corpuscular volume MCH: Mean corpuscular hemoglobin MCHC: Mean corpuscular hemoglobin concentration References Akhigbe, R

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Deisseroth AB, Zhang W, Cha Y, Yuan T, Chen H, Sims SH, Wedrychowski A, P-Q G, Huston LJ, Filaccio M, Claxton DF, Kornblau SM , Johnson EB, Howard OMZ, Andersson B, del Giglio A, Gressot L, Kantarjian HM, Talpaz M, Khouri I, Champlin RE, Andreeff M, Gaozza E, Seong DC, S-P S, Ellerson D, Hu G, Chou M

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