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[18] However, no clinical studies have examined the security and effectiveness of NAD+ treatment for addiction as of yet

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Controlled human trials exist, but they're limited in size, focused mostly on topical cosmetic use, and usually last only a few weeks or months. That means a lot of the exciting claims, especially around gene expression, systemic repair, and anti-aging effects, haven't been confirmed in large-scale human studies

GPX4 was first purified by Ursini and colleagues through biochemical technology [69]