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Urig, S., Lieske, J., Fritz-Wolf, K., Irmler, A

1 Introduction Tumor-associated macrophages (TAMs), a dominant immune cell population in the tumor microenvironment (TME), significantly influence cancer progression ( Ferroptosis represents a metabolically driven form of regulated cell death that is fundamentally distinct from apoptosis, necroptosis, and pyroptosis ( Figure 1

It should be noted that in certain cell types or cell lines, inhibition of GPX4 fails to induce ferroptosis, suggesting the existence of alternative mechanisms

Angermayer had told me that he expected two to five world records