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Individuals at risk of vitamin B12 deficiency include older adults, people with gastrointestinal disorders, those who have had gastrointestinal surgeries, individuals on a strict vegan diet, individuals who take metformin for blood sugar control, and people taking proton pump inhibitors for chronic heartburn

These parameters were also measured at the end-of-trial visit at week 111 (within 5 days either side of scheduled visit day)

We understand that timing and product integrity are critical for research

The compounds quinolinium scaffold mimics nicotinamides structure, allowing it to compete for the NNMT active site while avoiding interactions with other enzymes

Early studies suggested that AOD-9604 may increase fat metabolism without affecting insulin levels