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In a study of chronic kidney disease (CKD), overexpression of SIRT6 was found to activate the NRF2/HO-1 pathway

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As such, HDACs, a group of vital epigenetic targets manipulating gene transcription, are probably involved in the occurrence of epilepsy

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In this case, we urgently need to develop new targets for treatment and improve traditional treatment methods to increase the efficacy of drugs, reduce the side effects of drugs, and figure out the problem of drug resistance

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