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A.CorrealeJ.GravesJ.et al

In a rat model of carrageenan-induced inflammation, subcutaneous implantation of polyester sponges led to a steady increase in PGE within the first 24 h, whereas thromboxane A (TXA) and leukotriene B (LTB) peaked at 46 h and declined thereafter

The characteristic symptoms of sepsis are the development of systemic inflammation and multiple organ dysfunction up to the development of septic shock

M., Shatilla, A

Another key feature of this study is the use of full-length CSD and subregions modified to be water-soluble, thereby enhancing the likelihood they can be developed to treat human disease