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Hmg-coa reductase inhibitors induce apoptosis of lymphoma cells by promoting ros generation and regulating akt, erk and p38 signals via suppression of mevalonate pathway

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Moreover, using probucol (500 mg/day, P.O for 6 months) for secondary prevention in patients with CHD lowered the incidence of the patients primary endpoint (cardiovascular disease death, hospitalization rate), which may be partly due to its strong antioxidant capacity [245]

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It is involved in many processes in the body including tissue building and repair, making chemicals and proteins needed in the body, and also an essential component of the bodys natural defence system (immune system)