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Kamata et al., Drug Metabolism Disposition, 34:281-287, 2006 Many compounds or drugs contain functional groups that can be directly conjugated and thus do not require Phase I metabolism to create handles (nucleophiles) for conjugation

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Besides the above-mentioned endogenous sources of ROS, a growing list of potential lifestyles and environmental factors have been suggested to contribute to the extreme generation of ROS in semen

Available trials have lasted up to one week and report that the peptide may cause mild gastrointestinal issues, including nausea [3]

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