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How about things like the weather

Choline is an essential nutrient for our brains

10.1128/iai.01980-14 Infect

J., Sasaki, Y., DiAntonio, A

Nevertheless, most first-line drugs for the treatment of those disorders target the serotonin and/or dopamine systems either directly (e.g., in depression) or indirectly via modulation of GABA-A receptors