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L-pyroglutamic acid is a bioactive enantiomer in human body

Mu, F., Wang, W., Liu, L., Hu, N

And it's actually prescribed for what's called hypothalamic amenorrhea

24 h after the clamp removal, mice ( n = 8 sham and n = 8 AKI) were injected at the dose of 5 ml/kg via tail vein and were sacrificed 30 min after the injection