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J.et al

Gout is a major problem in the foot, but it can also involve many other joints

Annu Rev Plant Physiol Plant Mol Biol 49 : 249-279

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have demonstrated that mutations in the precore region of the hepatitis B virus (HBV) genome affected the coding of HBV e antigen (HBeAg), which was associated with severe immunological dysregulation in acute severe hepatitis[34, 35]