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Both PGE2 and PGI2 are pro-inflammatory prostanoids that increase vascular permeability, promote leukocyte infiltration and increase edema formation 4

Fucoidan enhanced the functioning of mitochondria and protected the brain by actively controlling the Nrf2 pathway

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312 Moreover, age serves as a significant risk factor, with the incidence of diabetes doubling for those over 65 years and increasing fourfold for individuals above 75 years old

144 Similarly, Pien Tze Huang, a traditional Chinese medicine, also exhibits protective effects against APAP-induced liver injury by significantly reducing levels of NLRP3 inflammasomes and proinflammatory cytokines