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This is significant since elevated KYN/TRP ratios and neuroactive metabolites like quinolinic acid are linked with symptoms in disorders, including ME/CFS

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The mechanism is selective NNMT inhibition reducing adipocyte methyl-flux toward 1-methylnicotinamide

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That may not seem like much, but even .10 BAC is a lot of alcohol for the body to absorb

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Go to the nub of the needle so it can go no further

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