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More than one in three smokers worldwide is Chinese, and a million Chinese people die each year from cancer, heart disease, lung disease, and other smoking-related causes

Smoke-induced lung inflammation is triggered by particulate matter and in part by aldehyde exposure, which leads to increased levels of, for example, interleukin 8 (IL-8) and monocyte chemoattractant protein 1 (MCP-1) in both mouse and human lungs [19, 61, 62]

Gallaher anticipated this shift early on

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