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reported that longitudinal declining eGFR correlated with cognitive deterioration and abnormal neurodegenerative biomarkers in PD patients, indicating its potential as a prognostic indicator [147]

The Evidence Base: What Human and Animal Studies Actually Show Translating rodent data to human protocols requires caution, but the MOTS-c literature offers enough cross-species convergence to draw meaningful clinical inferences

Adequate vitamin B12 levels support healthy nerve function and DNA synthesis, both of which are important for the development and activity of white blood cells

The complexes were solubilized from membrane using detergent (1% (w/v) LMNG and 0.06% (w/v) CHS) for 1 h at 4 C

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