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WSAVA Liver Standardization Group eds

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350,351 When diseases advance, mitochondrial function deteriorates due to multiple factors, impairing the ability of mitochondria to generate ATP, increasing ROS production, and potentially enhancing mitochondrial membrane permeability, thus promoting inflammation and cell death

Get started In clinical trials of the oral Wegovy (semaglutide) pill, participants taking the medication with diet and exercise achieved average weight loss of about 14%17% over ~64 weeks compared with ~2% with placebo

The presence of minor constituents such as 2-hexenal, an ,-unsaturated aldehyde capable of forming DNA adducts, which may contribute to carcinogenic risk when exposure is chronic (73)