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Furthermore, fibrotic lesions often exhibit increased innervation, and the fibrosis itself can entrap or irritate nerve fibers, leading to neuropathic pain components [112]

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RNA concentrations were quantified using a NanoDrop 1000 Spectrophotometer (Thermo Fisher Scientific) and RNA quality was determined using a Bioanalyzer Agilent 2100 (Agilent Technologies)